IL-17A-IN-5
IL-17A-IN-5 (Compound 9) is an orally active IL-17A inhibitor. IL-17A-IN-5 demonstrates a clear dose-dependent inhibition of arthritis[1].
Product Specifications
UNSPSC
12352005
Target
Interleukin Related
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
COC[C@@H](N1C[C@H](NC1=O)C(F)(F)F)C2=NN3C=C(N=C3C=C2)[C@H]([C@H]4CC[C@@H](C)CC4)NC(OC5CC(F)(F)C5)=O
Molecular Formula
C26H33F5N6O4
Molecular Weight
588.57
References & Citations
[1]Deng X, et al. The Critical and Unexpected Role of a Methyl Group in Interleukin-17A Inhibitors[J]. bioRxiv, 2025: 2025.10. 02.680113.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-17
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