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NMDAR modulator 1

NMDAR modulator 1 (Compound 12) is a positive, allosteric GluN1/GluN2B receptor modulator. NMDAR modulator 1 enhances NMDAR current. NMDAR modulator 1 can be used in the research of psychiatric disorders[1].

Product Specifications

UNSPSC

12352211

Target

IGluR

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

CCO/N=C(C1CC[C@@]2([H])[C@]3([H])CC=C4C[C@H](CC[C@@]4([C@@]3([H])CC[C@]12C)C)OC(CCCC(O)=O)=O)\C

Molecular Formula

C28H43NO5

Molecular Weight

473.64

References & Citations

[1]Adla S K, et al. Positive Modulators of N-Methyl-D-Aspartate Receptor: Structure-Activity Relationship Study on Steroidal C-17 and C-20 Oxime Ethers. bioRxiv, 2025: 2025.10. 03.680025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NMDA Receptor

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