SLC6A19-IN-3
SLC6A19-IN-3 (Compound 83-P1-P2) is a potent, selective and orally active SLC6A19 inhibitor with an IC50 of 28 nM. SLC6A19-IN-3 can block SLC6A19-mediated transmembrane transport of phenylalanine, reducing intestinal absorption of phenylalanine from food and renal tubular reabsorption of phenylalanine. SLC6A19-IN-3 can be used for the research of metabolic disease, such as phenylketonuria[1].
Product Specifications
CAS Number
[3104477-57-5]
UNSPSC
12352005
Target
Amino acid Transporter
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Metabolic Disease
Smiles
CNC(N1C[C@@H](C[C@H]2C[C@H]21)N(C3CC3)C(NCC#CC4=CC=CC(Cl)=C4)=O)=O
Molecular Formula
C21H25ClN4O2
Molecular Weight
400.90
References & Citations
[1]Chene Zhang, et al. Slc6a19 inhibitor compound, pharmaceutical composition, preparation method, and use. WO2025214397. 2025-10-16
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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