Axl-IN-20
Axl-IN-20 (Compound w11) is a selective, orally active AXL inhibitor, with an IC50 of 5 nM. Axl-IN-20 has antitumor activity against hematological malignancies[1].
Product Specifications
CAS Number
[2487649-59-0]
UNSPSC
12352005
Target
TAM Receptor
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
CN1C=C(C2=C1N=CN=C2N)C3=CC=C(C=C3)NC(C4=C5CCCN5N(C4=O)C6=CC=CC=C6)=O
Molecular Formula
C26H23N7O2
Molecular Weight
465.51
References & Citations
[1]Sun M, et al. Structure-based drug discovery of novel penta- or hexa-bicyclo-pyrazolone derivatives as potent and selective AXL inhibitors. RSC Med Chem. 2025 Aug 9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7164397 Inquire
Rabbit anti-Human immunodeficiency virus type 1 group M subtype D (isolate ELI)(HIV-1) gag-pol Polyclonal Antibody
Ask
View Details