SARS-CoV-2 Mpro-IN-51

SARS-CoV-2 Mpro-IN-51 is a SARS-CoV-2 Mpro inhibitor (IC50 = 26 nM) . SARS-CoV-2 Mpro-IN-51 has inhibitory effects on the triple mutant L50F/E166A/L167F. SARS-CoV-2 Mpro-IN-51 can be used for research on viral infections[1].

Product Specifications

CAS Number

[2648754-84-9]

UNSPSC

12352005

Target

SARS-CoV; Virus Protease

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

[H]C([C@@H](NC([C@@H](NC(C1=CC2=C(N1)C=CC=C2OC)=O)CC3CC3)=O)C[C@@H]4CCNC4=O)(S(=O)(O[Na])=O)O

Molecular Formula

C23H29N4NaO8S

Molecular Weight

544.55

References & Citations

[1]Fischer C, et al. Structural insights into the nirmatrelvir-resistant SARS-CoV-2 Mpro L50F/E166A/L167F triple mutant-inhibitor-complex reveal strategies for next generation coronaviral inhibitor design. RSC Med Chem. 2025 Aug 15;16 (10) :5032-5040.