IAN-15B

IAN-15B has high selectivity and potent ST6GAL1 inhibitors (IC50 = 3.3 μM) . IAN-15B has significant anti migratory and anti angiogenic effects. IAN-15B can be used in the research of cancer such as breast cancer[1].

Product Specifications

UNSPSC

12352005

Target

Sialyltransferase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

[H][C@]12CC[C@@]3([C@H](CC[C@]3([C@@]1(CC[C@@]4(C[C@@H](CC[C@]24C)O)[H])[H])[H])[C@@H](CCC(N[C@@H](C(O)=O)CC(C5=CNC6=C5C=C(C=C6)N=[N+]=[N-])C7=CNC8=C7C=C(C=C8)N=[N+]=[N-])=O)C)C

Molecular Formula

C44H55N9O4

Molecular Weight

773.97

References & Citations

[1]Concio CAP, et al. Novel lithocholic acid-diindolylmethane hybrids as potent sialyltransferase inhibitors targeting triple-negative breast cancer: a molecular hybridization approach. RSC Med Chem. 2025 Aug 28;16 (10) :5070-5083.