SARS-CoV-2 nsp14-IN-8
SARS-CoV-2 nsp14-IN-8 (Compound 26) is a SARS-CoV-2 nsp14 inhibitor, with an IC50 of 53 nM. SARS-CoV-2 nsp14-IN-8 shows IC50 values of 170 nM, 8 nM, 21 nM against SARS-CoV-1 nsp14, HCoV-NL63 nsp14, HCoV-229E nsp14, respectively. SARS-CoV-2 nsp14-IN-8 can be used in the research of Coronavirus infection[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O[C@H]1[C@H](N2C(N=CN=C3N)=C3N=C2)C[C@H](CSC4=NC5=C(S4)C=CC=C5)[C@H]1O
Molecular Formula
C18H18N6O2S2
Molecular Weight
414.50
References & Citations
[1]Georgiou I, et al. Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase. bioRxiv, 2025: 2025.09. 30.679521.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470633-100 1x 100 µL
Von Willebrand Factor (3E2D10), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC941231-100 1x 100 µL
Eosinophil Peroxidase (AHE-1), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041073-500 1x 500 µL
HLA-Aw32 & HLA-A25 (MHC I) (CATA-1), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940149-100 1x 100 µL
CD106 / VCAM1 (1.4C3), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC740096-100 1x 100 µL
Histone H1 (AE-4), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC942337-500 1x 500 µL
TRAcP (Tartrate-Resistant Acid Phosphatase) (Hairy Cell Leukemia Marker) (rACP5/1070), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details