E3 Ligase Ligand-linker Conjugate 213
E3 Ligase Ligand-linker Conjugate 213 is an E3 ligase ligand-linker conjugate (E3 ligase ligand-linker conjugate) consisting of an E3 ubiquitinase CRBN ligand (HY-A0003) and a linker (HY-W008820) . E3 Ligase Ligand-linker Conjugate 213 can be used to synthesize PSP-0119 (HY-179094) [1].
Product Specifications
CAS Number
[1334496-37-5]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Others
Smiles
O=C(O)CCCC(NC1=CC=CC2=C1CN(C2=O)C3CCC(NC3=O)=O)=O
Molecular Formula
C18H19N3O6
Molecular Weight
373.36
References & Citations
[1]Khazan N, et al. PSP-0119: Targeted IRAK4 Degradation as a Novel Therapeutic Strategy for FLT3-Mutant AML. bioRxiv [Preprint]. 2025 Oct 2:2025.09.30.679569.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
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