E3 Ligase Ligand-linker Conjugate 213

E3 Ligase Ligand-linker Conjugate 213 is an E3 ligase ligand-linker conjugate (E3 ligase ligand-linker conjugate) consisting of an E3 ubiquitinase CRBN ligand (HY-A0003) and a linker (HY-W008820) . E3 Ligase Ligand-linker Conjugate 213 can be used to synthesize PSP-0119 (HY-179094) [1].

Product Specifications

CAS Number

[1334496-37-5]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Others

Smiles

O=C(O)CCCC(NC1=CC=CC2=C1CN(C2=O)C3CCC(NC3=O)=O)=O

Molecular Formula

C18H19N3O6

Molecular Weight

373.36

References & Citations

[1]Khazan N, et al. PSP-0119: Targeted IRAK4 Degradation as a Novel Therapeutic Strategy for FLT3-Mutant AML. bioRxiv [Preprint]. 2025 Oct 2:2025.09.30.679569.