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CU-TZD-20

CU-TZD-20 is a PARP-1 inhibitor. CU-TZD-20 has a high affinity for binding to the PARP-1 catalytic domain and good structural stability. CU-TZD-20 competitively occupies NAD+ binding sites and forms stable interactions with key catalytic residues. CU-TZD-20 can be used for cancer research[1].

Product Specifications

UNSPSC

12352005

Target

PARP

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Cancer

Smiles

OC1=C2C(OC(C=C2)=O)=C(O)C(NC(C3NC(/C(S3)=C/C4=CC(O)=C(OC)C(O)=C4)=O)=O)=C1

Molecular Formula

C21H16N2O9S

Molecular Weight

472.42

References & Citations

[1]Rambabu P, et al. Energy Landscape Mapping–Guided Rational Design of Coumarin‐Based PARP‐1 Inhibitors[J]. ChemistrySelect, 2025, 10 (40) : e03552.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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