CU-TZD-20
CU-TZD-20 is a PARP-1 inhibitor. CU-TZD-20 has a high affinity for binding to the PARP-1 catalytic domain and good structural stability. CU-TZD-20 competitively occupies NAD+ binding sites and forms stable interactions with key catalytic residues. CU-TZD-20 can be used for cancer research[1].
Product Specifications
UNSPSC
12352005
Target
PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
OC1=C2C(OC(C=C2)=O)=C(O)C(NC(C3NC(/C(S3)=C/C4=CC(O)=C(OC)C(O)=C4)=O)=O)=C1
Molecular Formula
C21H16N2O9S
Molecular Weight
472.42
References & Citations
[1]Rambabu P, et al. Energy Landscape Mapping–Guided Rational Design of Coumarin‐Based PARP‐1 Inhibitors[J]. ChemistrySelect, 2025, 10 (40) : e03552.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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