Lisinopril

Lisinopril (MK-521) is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks.

Product Specifications

CAS Number

[76547-98-3]

Product Name Alternative

MK-521

UNSPSC

12352005

Hazard Statement

H315, H319, H335, H361

Target

Angiotensin-converting Enzyme (ACE)

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/lisinopril.html

Purity

99.96

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(O)[C@H]1N(C([C@H](CCCCN)N[C@H](C(O)=O)CCC2=CC=CC=C2)=O)CCC1

Molecular Formula

C21H31N3O5

Molecular Weight

405.49

Precautions

H315, H319, H335, H361

References & Citations

[1]Andujar-Sanchez, M., V. Jara-Perez, and A. Camara-Artigas, Thermodynamic determination of the binding constants of angiotensin-converting enzyme inhibitors by a displacement method. FEBS Lett, 2007. 581 (18) : p. 3449-54.|[2]Song, J.C. and C.M. White, Clinical pharmacokinetics and selective pharmacodynamics of new angiotensin converting enzyme inhibitors: an update. Clin Pharmacokinet, 2002. 41 (3) : p. 207-24.