DAPK1 ligand-1
DAPK1 ligand-1 is a PROTAC target protein ligand that can be used for synthesis of PROTACs, such as PROTAC DAPK1 Degrader-1 (HY-179055) . PROTAC DAPK1 Degrader-1 is a potent LAG-3 PROTAC degrader with neuroprotective activity[1].
Product Specifications
CAS Number
[3057532-78-9]
UNSPSC
12352005
Target
DAPK; Target Protein Ligand-Linker Conjugates
Related Pathways
Apoptosis; PROTAC
Field of Research
Neurological Disease
Smiles
O=C(C1=CC=CC(N2N=CC3=C2N=C(NC3=O)SC(C(N)=O)C)=C1)O
Molecular Formula
C15H13N5O4S
Molecular Weight
359.36
References & Citations
[1]Wu X, et al. Design, synthesis, and biological evaluation of death-associated protein kinase 1 PROTACs. Bioorg Chem. 2025 Oct;165:109044.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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