E3 Ligase Ligand-linker Conjugate 212

E3 Ligase Ligand-linker Conjugate 212 is a PROTAC E3 ligase-linker conjugate that can be used for synthesis of PROTACs, such as PROTAC IKZF1/3 Degrader-1 (HY-179075) . PROTAC IKZF1/3 Degrader-1 is a potent IKZF1/3 PROTAC degrader with neuroprotective activity[1].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(N(C1=O)C2CCC(NC2=O)=O)C3=C1C=CC=C3NCCC(CC4)CCN4CC5CCNCC5

Molecular Formula

C26H35N5O4

Molecular Weight

481.59

References & Citations

[1]Jin Y, et al. Modular PROTAC/IMiD Bifunctional Molecule Design for the Degradation of Synergistic Targets in the Treatment of Lymphoma. J Med Chem. 2025 Oct 23;68 (20) :21249-21281.