IKZF1/3 ligand-1

IKZF1/3 ligand-1 is a PROTAC target protein ligand that can be used for synthesis of PROTACs, such as PROTAC IKZF1/3 Degrader-1 (HY-179075) . PROTAC IKZF1/3 Degrader-1 is a potent IKZF1/3 PROTAC degrader with neuroprotective activity[1].

Product Specifications

CAS Number

[2230408-75-8]

UNSPSC

12352005

Target

IKZF Family; Target Protein Ligand-Linker Conjugates

Related Pathways

Immunology/Inflammation; PROTAC

Field of Research

Cancer

Smiles

CNC(COC1=CC2=C(N(C1=O)C)C=CC(NC3=NC(Cl)=NC=C3Cl)=C2)=O

Molecular Formula

C17H15Cl2N5O3

Molecular Weight

408.24

References & Citations

[1]Jin Y, et al. Modular PROTAC/IMiD Bifunctional Molecule Design for the Degradation of Synergistic Targets in the Treatment of Lymphoma. J Med Chem. 2025 Oct 23;68 (20) :21249-21281.