IKZF1/3 ligand-1
IKZF1/3 ligand-1 is a PROTAC target protein ligand that can be used for synthesis of PROTACs, such as PROTAC IKZF1/3 Degrader-1 (HY-179075) . PROTAC IKZF1/3 Degrader-1 is a potent IKZF1/3 PROTAC degrader with neuroprotective activity[1].
Product Specifications
CAS Number
[2230408-75-8]
UNSPSC
12352005
Target
IKZF Family; Target Protein Ligand-Linker Conjugates
Related Pathways
Immunology/Inflammation; PROTAC
Field of Research
Cancer
Smiles
CNC(COC1=CC2=C(N(C1=O)C)C=CC(NC3=NC(Cl)=NC=C3Cl)=C2)=O
Molecular Formula
C17H15Cl2N5O3
Molecular Weight
408.24
References & Citations
[1]Jin Y, et al. Modular PROTAC/IMiD Bifunctional Molecule Design for the Degradation of Synergistic Targets in the Treatment of Lymphoma. J Med Chem. 2025 Oct 23;68 (20) :21249-21281.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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