LAG-3 degrader 1
LAG-3 degrader 1 is a PROTAC target protein ligand that can be used for synthesis of PROTACs, such as LAG-3 PROTAC-1. LAG-3 PROTAC-1 is a potent LAG-3 PROTAC degrader with anti-tumor activity[1].
Product Specifications
CAS Number
3009770-86-6
UNSPSC
12352005
Target
LAG-3; Target Protein Ligand-Linker Conjugates
Related Pathways
Immunology/Inflammation; PROTAC
Field of Research
Cancer
Smiles
NC([C@H]([C@@H](C1=CC=CC=C1)C2)CN2CC3=CC=CC=N3)=O
Molecular Formula
C17H19N3O
Molecular Weight
281.35
References & Citations
[1]Vázquez NG, et al. Design and validation of the first-in-class PROTACs for targeted degradation of the immune checkpoint LAG-3. Bioorg Med Chem Lett. 2025 Oct 4;130:130428.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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