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LAG-3 degrader 1

LAG-3 degrader 1 is a PROTAC target protein ligand that can be used for synthesis of PROTACs, such as LAG-3 PROTAC-1. LAG-3 PROTAC-1 is a potent LAG-3 PROTAC degrader with anti-tumor activity[1].

Product Specifications

CAS Number

3009770-86-6

UNSPSC

12352005

Target

LAG-3; Target Protein Ligand-Linker Conjugates

Related Pathways

Immunology/Inflammation; PROTAC

Field of Research

Cancer

Smiles

NC([C@H]([C@@H](C1=CC=CC=C1)C2)CN2CC3=CC=CC=N3)=O

Molecular Formula

C17H19N3O

Molecular Weight

281.35

References & Citations

[1]Vázquez NG, et al. Design and validation of the first-in-class PROTACs for targeted degradation of the immune checkpoint LAG-3. Bioorg Med Chem Lett. 2025 Oct 4;130:130428.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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