Apoptosis inducer 51
Apoptosis inducer 51 (Compound 5d) is an apoptosis inducer. Apoptosis inducer 51 exhibits strong inhibitory activity against MDA-MB-231 cells. Apoptosis inducer 51 inhibits cell invasion and migration, induces G2/M phase cell cycle arrest and cell apoptosis. Apoptosis inducer 51 causes DNA damage, ROS burst and mitochondrial membrane potential (MMP) collapse. Apoptosis inducer 51 can be used for the study of triple-negative breast cancer.
Product Specifications
UNSPSC
12352005
Target
Apoptosis; DNA/RNA Synthesis; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Smiles
[H][C@@]12CC[C@]3([H])[C@]([C@@]1(C)CC[C@H](OC(CCCNC(CCCC4=CC=C(N(CCCl)CCCl)C=C4)=O)=O)C2)([H])CC([C@]5(C)[C@H]6[C@H](C)[C@]7(OC[C@H](C)CC7)O[C@H]6C[C@]53[H])=O
Molecular Formula
C45H66Cl2N2O6
Molecular Weight
801.92
References & Citations
[1]Su W, et al. Hecogenin nitrogen mustard hybrids with improved anti-breast cancer activity: Design, synthesis, and biological evaluation. Bioorg Chem. 2025 Oct;165:109032.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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