Androgen receptor-IN-7
Androgen receptor-IN-7 is a potent androgen receptor (AR) inhibitor. Androgen receptor-IN-7 exhibits potent anticancer activity against PC-3 cells (IC50 =370.37 nM) and LNCaP cells via both AR-dependent and AR-independent pathways. Androgen receptor-IN-7 induces ROS production in PC-3 cells. Androgen receptor-IN-7 can be used for prostate cancer research[1].
Product Specifications
CAS Number
401580-43-6
UNSPSC
12352005
Target
Androgen Receptor; Reactive Oxygen Species (ROS)
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
FC1=CC=C(C=C1)C2=NC(C3=CC=CC=C3)=NO2
Molecular Formula
C14H9FN2O
Molecular Weight
240.23
References & Citations
[1]Kumar S, et al. Oxadiazole derivatives as potent androgen receptor inhibitors: Design, synthesis, and anticancer evaluation. Bioorg Chem. 2025 Oct;165:109060.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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