Dyrk1A-IN-14
Dyrk1A-IN-14 (Compound 45,934,388) is a Dyrk1A inhibitor with a pIC50 value of 6.16. Dyrk1A-IN-14 is predicted to have good oral bioavailability and blood-brain barrier penetration ability (AI Drug Lab) . Dyrk1A-IN-14 can be used for the study of Alzheimer's disease[1].
Product Specifications
CAS Number
[1209977-31-0]
UNSPSC
12352005
Target
DYRK
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Neurological Disease
Smiles
C=C1OC2=C(C(C)=C(C(O)=C2CO)C(O)=O)OC3=C1C(C)=CC(O)=C3C=O
Molecular Formula
C19H16O8
Molecular Weight
372.33
References & Citations
[1]Makinde IA, et al. Identification of novel DYRK1A inhibitors as treatment options for alzheimer's disease through comprehensive in silico approaches. Sci Rep. 2025 Oct 15;15 (1) :36114.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DYRK1
Curated Selection
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