APG-7
APG-7 binds to the TLR4/MD-2 interface, thereby inhibiting NO production (IC50 of 24.2 μg/mL). APG-7 is an Apigenin derivative. APG-7 has low toxicity to the 3T3 fibroblast cell line. APG-7 can be used for the study of oxidative stress and inflammation[1].
Product Specifications
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Smiles
O[C@@H]1[C@@H](OC2=CC=C(C=C2)C3=CC(C4=C(C=C(C=C4O3)O)O)=O)O[C@@H](COC(/C=C/C5=CC=C(C=C5)O)=O)[C@H](O)[C@@H]1O
Molecular Formula
C30H26O12
Molecular Weight
578.52
References & Citations
[1]Soomro S, et al. Apigenin and its derivative modulate nitric oxide production and interfere with TLR4-M2: In-vitro and in-silico insights. Bioorg Chem. Published online October 4, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR4
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
VAng-Lsx05930-500gEcoli 500 µg (E. coli)
Recombinant Candida Albicans SEC13 Protein (aa 1-298)
Sign In for Pricing
View Details 
GTR10385554 96 Well
Porcine Olfactory receptor 51E1 (OR51E1) ELISA kit
Sign In for Pricing
View Details 
E28G2316 100 µL
Topoisomerase II alpha (Phospho Thr1343) (14J5) Rabbit Monoclonal Antibody
Sign In for Pricing
View Details