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Xanthine oxidase-IN-19

Xanthine oxidase-IN-19 (Compound 13i) is an orally effective inhibitor of xanthine oxidase (XO), with an IC50 of 0.2 μM. Xanthine oxidase-IN-19 can significantly reduce serum uric acid levels in acute hyperuricemia rat models. Xanthine oxidase-IN-19 can be used for the study of acute hyperuricemia[1].

Product Specifications

CAS Number

[3055301-22-6]

Target

Xanthine Oxidase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

O=C(C1=NN=C(C2=CC3=C(N(C4CCCC4)C=C3C#N)C=C2)C=C1)O

Molecular Formula

C19H16N4O2

Molecular Weight

332.36

References & Citations

[1]Li S, et al. Design, synthesis, and evaluation of N-substituted indolyl-diazine derivatives as potent xanthine oxidase inhibitors. Bioorg Chem. 2025 Oct 9;166:109076.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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