NOD2 agonist 4
NOD2 agonist 4 (Compound 12b) is a potent NOD2 agonist with an EC50 of 44.1 nM. NOD2 agonist 4 induces cytokine production (MCP-1, IL-6 and IL-8) in peripheral blood mononuclear cells (PBMCs), both alone and in combination with Lipopolysaccharide (LPS). NOD2 agonist 4 can be used for the studies of NOD2-targeted immunomodulator or vaccine adjuvant[1].
Product Specifications
UNSPSC
12352211
Target
Interleukin Related; NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
[][Fe][].O=C(Cc1cccc1)NCC(N[C@@H](C(C)C)C(N[C@H](CCC(OCC)=O)C(OCC)=O)=O)=O.c2cccc2
Molecular Formula
C28H39FeN3O7
Molecular Weight
585.47
References & Citations
[1]Car Z, et al. Ferrocene-Containing Desmuramylpeptides Adopt A Flexible Conformation and Exhibit NOD2 Agonistic Activity. Organometallics. 2025 Oct 22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-6; IL-8; NOD2
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