(S) -STO021
(S) -STO021 is a highly selective, orally effective ERβ agonist. (S) -STO021 has a dual activity of inhibiting osteoclast activity and promoting osteoblast activity. (S) -STO021 can be used for research on osteoporosis[1].
Product Specifications
CAS Number
[3058379-08-8]
UNSPSC
12352128
Target
Estrogen Receptor/ERR
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Smiles
O=P(OCC)(OCC)OC1=CC=C(C=C1)[C@@H]2C(C3=CC(O)=CC(O)=C3)=C(OP(OCC)(OCC)=O)C4=CC(O)=CC(O)=C24
Molecular Formula
C29H34O12P2
Molecular Weight
636.52
References & Citations
[1]Peng C, et al. Discovery of Novel Selective Estrogen Receptor β (SERβ) Agonist (S) -STO021 as an Antiosteoporosis Candidate with Dual Functions of Inhibiting Osteoclastogenesis and Activating Osteoblastogenesis. J Med Chem. 2025 Nov 13;68 (21) :22715-22737.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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