(S) -STO021

(S) -STO021 is a highly selective, orally effective ERβ agonist. (S) -STO021 has a dual activity of inhibiting osteoclast activity and promoting osteoblast activity. (S) -STO021 can be used for research on osteoporosis[1].

Product Specifications

CAS Number

[3058379-08-8]

UNSPSC

12352128

Target

Estrogen Receptor/ERR

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Inflammation/Immunology

Smiles

O=P(OCC)(OCC)OC1=CC=C(C=C1)[C@@H]2C(C3=CC(O)=CC(O)=C3)=C(OP(OCC)(OCC)=O)C4=CC(O)=CC(O)=C24

Molecular Formula

C29H34O12P2

Molecular Weight

636.52

References & Citations

[1]Peng C, et al. Discovery of Novel Selective Estrogen Receptor β (SERβ) Agonist (S) -STO021 as an Antiosteoporosis Candidate with Dual Functions of Inhibiting Osteoclastogenesis and Activating Osteoblastogenesis. J Med Chem. 2025 Nov 13;68 (21) :22715-22737.