Carnosol analog 1
Carnosol analog 1 (Compound 10) is a derivative of carnosol. Carnosol analog 1 attenuates myotube atrophy (67.08% reversal) and adipocyte lipolysis in C26 tumor-conditioned models. Carnosol analog 1 alleviates cachexia-related weight loss without altering tumor progression in C26 tumor-bearing mice. Carnosol analog 1 can be used for the study of cancer cachexia[1].
Product Specifications
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Field of Research
Cancer
Smiles
BrC1=CC=C(C2=NC3=C(C([C@@]4(CCCC5(C)C)C5CC6OC4=O)=C6C=C3C(C)C)O2)C=C1
Molecular Formula
C27H28BrNO3
Molecular Weight
494.42
References & Citations
[1]Wang J, et al. Synthesis, structure-activity relationships of carnosol derivatives for cancer-associated cachexia. Bioorg Med Chem Lett. 2025 Sep 27;130:130420.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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