5-HT7R antagonist 5
5-HT7R antagonist 5 (Compound (R) -4) is a 5-HT7AR antagonist, with a Ki of 46.4 nM. 5-HT7R antagonist 5 shows anticancer effects against prostate cancer[1].
Product Specifications
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cancer
Smiles
CN1[C@@]2([H])C3=C(C(C(SC(N)=N4)=C4C=C5)=C5C2)C=CC=C3CC1
Molecular Formula
C18H17N3S
Molecular Weight
307.41
References & Citations
[1]Okpattah D, et al. Synthesis and evaluation of aporphinoid 5-HT7AR ligands as inhibitors of PC3 prostate cancer cell growth. Bioorg Med Chem Lett. 2025 Dec 1;128:130328.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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