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DENV-IN-14

DENV-IN-14 (Compound 3c) is a thiazole hydrazone derivative with anti-dengue virus (DENV) activity with an EC50 of 0.01 μM and the selectivity index (SI) of 200. DENV-IN-14 exhibits rapid plasma clearance and its metabolic stability is limited. DENV-IN-14 can be used for research on dengue fever[1].

Product Specifications

UNSPSC

12352005

Target

Dengue Virus; Flavivirus

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

ClC1=CC=C(C2=CSC(N/N=C(C3=CC(O)=CC(O)=C3)\C)=N2)C=C1

Molecular Formula

C17H14ClN3O2S

Molecular Weight

359.83

References & Citations

[1]Siddique MUM, et al. Synthesis and antiviral activity of thiazolyl hydrazones against dengue virus. Bioorg Med Chem Lett. 2025 Oct 10;130:130436.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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