DENV-IN-14
DENV-IN-14 (Compound 3c) is a thiazole hydrazone derivative with anti-dengue virus (DENV) activity with an EC50 of 0.01 μM and the selectivity index (SI) of 200. DENV-IN-14 exhibits rapid plasma clearance and its metabolic stability is limited. DENV-IN-14 can be used for research on dengue fever[1].
Product Specifications
UNSPSC
12352005
Target
Dengue Virus; Flavivirus
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
ClC1=CC=C(C2=CSC(N/N=C(C3=CC(O)=CC(O)=C3)\C)=N2)C=C1
Molecular Formula
C17H14ClN3O2S
Molecular Weight
359.83
References & Citations
[1]Siddique MUM, et al. Synthesis and antiviral activity of thiazolyl hydrazones against dengue virus. Bioorg Med Chem Lett. 2025 Oct 10;130:130436.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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