HIV-1-IN-90
HIV-1-IN-90 is an orally effective HIV inhibitor. HIV-1-IN-90 has a CC50 of 17.16 µM in MT-4 cells. HIV-1-IN-90 exhibits potent inhibitory activity against multiple drug-resistant HIV-1 strains. HIV-1-IN-90 has good security. HIV-1-IN-90 can be used for research on HIV virus infection[1].
Product Specifications
UNSPSC
12352005
Target
HIV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CC1=CC(/C=C/C#N)=CC(C)=C1OC2=CC(N)=NC(NC3CCN(CC3)CC4=CC=NC=C4)=N2
Molecular Formula
C26H29N7O
Molecular Weight
455.55
References & Citations
[1]Ji X, et al. Structure- and Privileged Fragment-Based Iterative Optimization: Discovery of 2,4-Disubstituted-6-aminopyrimidines as Novel HIV-1 NNRTIs with Potent Activity against Drug-Resistant Strains and Favorable Safety Profiles. J Med Chem. 2025 Oct 20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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