HIV-1-IN-90

HIV-1-IN-90 is an orally effective HIV inhibitor. HIV-1-IN-90 has a CC50 of 17.16 µM in MT-4 cells. HIV-1-IN-90 exhibits potent inhibitory activity against multiple drug-resistant HIV-1 strains. HIV-1-IN-90 has good security. HIV-1-IN-90 can be used for research on HIV virus infection[1].

Product Specifications

UNSPSC

12352005

Target

HIV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

CC1=CC(/C=C/C#N)=CC(C)=C1OC2=CC(N)=NC(NC3CCN(CC3)CC4=CC=NC=C4)=N2

Molecular Formula

C26H29N7O

Molecular Weight

455.55

References & Citations

[1]Ji X, et al. Structure- and Privileged Fragment-Based Iterative Optimization: Discovery of 2,4-Disubstituted-6-aminopyrimidines as Novel HIV-1 NNRTIs with Potent Activity against Drug-Resistant Strains and Favorable Safety Profiles. J Med Chem. 2025 Oct 20.