Apelin agonist 2
Apelin agonist 2 is an orally effective APLNR agonist. Apelin agonist 2 can significantly inhibit the accumulation of cAMP (EC50 = 10 nM) . Apelin agonist 2 exhibits a significant improvement in glucose tolerance. Apelin agonist 2 can be used to study metabolic diseases such as diabetes[1].
Product Specifications
UNSPSC
12352005
Target
Apelin Receptor (APJ)
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease
Smiles
ClC1=CN=C(C(F)(C2=NN=C(C3=CN(C(CCCC)=N3)C4=C(C=CC=N4)C(F)(F)F)O2)F)N=C1
Molecular Formula
C20H15ClF5N7O
Molecular Weight
499.82
References & Citations
[1]Narayanan S, et al. Development of Central Nervous System-Penetrant Apelin Receptor Agonists. J Med Chem. 2025 Oct 20.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC881045-100 1x 100 µL
CD16 (C16/1045), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880096-100 1x 100 µL
Histone H1 (AE-4), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940413-100 1x 100 µL
Chromogranin A (CHGA/413), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940940-100 1x 100 µL
Glucose Regulated Protein 94 (GRP94) (9G10.F8.2), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940218-500 1x 500 µL
CD100 (Semaphorin-4D) (A8), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details