α, δ-NAG
α, δ-NAG is an orally active glutaminase-resistant less-hydrolyzable L-Glutamine derivative. α, δ-NAG is a G protein-coupled receptor (GPCR) allosteric modulator. α, δ-NAG suppresses neutrophilic airway inflammation by activating the GPCR/ERK/MKP-1 pathway. α, δ-NAG can be used for the researches of inflammation and immunology, such as asthma[1].
Product Specifications
CAS Number
3051899-13-6
UNSPSC
12352211
Target
Drug Derivative; ERK; Phosphatase; Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; Metabolic Enzyme/Protease; Others; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(NC(C)=O)CC[C@H](C(O)=O)NC(C)=O
Molecular Formula
C9H14N2O5
Molecular Weight
230.22
References & Citations
[1]Kim J M, et al. α, δ-N-Acetyl-glutamine Suppresses Neutrophilic Airway Inflammation by Activating the G Protein-Coupled Receptor/Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase Phosphatase 1 Pathway[J]. ACS Pharmacology & Translational Science, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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