α, δ-NAG
α, δ-NAG is an orally active glutaminase-resistant less-hydrolyzable L-Glutamine derivative. α, δ-NAG is a G protein-coupled receptor (GPCR) allosteric modulator. α, δ-NAG suppresses neutrophilic airway inflammation by activating the GPCR/ERK/MKP-1 pathway. α, δ-NAG can be used for the researches of inflammation and immunology, such as asthma[1].
Product Specifications
CAS Number
3051899-13-6
UNSPSC
12352211
Target
Drug Derivative; ERK; Phosphatase; Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; Metabolic Enzyme/Protease; Others; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(NC(C)=O)CC[C@H](C(O)=O)NC(C)=O
Molecular Formula
C9H14N2O5
Molecular Weight
230.22
References & Citations
[1]Kim J M, et al. α, δ-N-Acetyl-glutamine Suppresses Neutrophilic Airway Inflammation by Activating the G Protein-Coupled Receptor/Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase Phosphatase 1 Pathway[J]. ACS Pharmacology & Translational Science, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6194898-01 0.1 mL
CDH11 (Cadherin 11, Type 2, OB-Cadherin (Osteoblast), CAD11, CDHOB, OB, OSF-4) (MaxLight 405)
Sign In for Pricing
View Details MBS6194898-02 5x 0.1 mL
CDH11 (Cadherin 11, Type 2, OB-Cadherin (Osteoblast), CAD11, CDHOB, OB, OSF-4) (MaxLight 405)
Sign In for Pricing
View Details 