Microtubule-IN-13
Microtubule-IN-13 is a microtubule inhibitor. Microtubule-IN-13 interferes with microtubule dynamics, leading to defects in the mitotic spindle and persistent mitotic arrest. Microtubule-IN-13 exhibits potent cytotoxicity against multiple cancer cell lines (IC50 = 0.3-2.7 μM) . Microtubule-IN-13 can be used for cancer research[1].
Product Specifications
UNSPSC
12352005
Target
Microtubule/Tubulin
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(C1=CC=C(C=C1F)C(F)(F)F)NC2=C(C3=CC=CC=C3NC2=O)O
Molecular Formula
C17H10F4N2O3
Molecular Weight
366.27
References & Citations
[1]Abushaikha G M, et al. Identification and Preliminary Characterization of a Novel Tasquinimod Analog that Unexpectedly Induces Mitotic Arrest by Alteration of Microtubule Dynamics[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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