Microtubule-IN-13

Microtubule-IN-13 is a microtubule inhibitor. Microtubule-IN-13 interferes with microtubule dynamics, leading to defects in the mitotic spindle and persistent mitotic arrest. Microtubule-IN-13 exhibits potent cytotoxicity against multiple cancer cell lines (IC50 = 0.3-2.7 μM) . Microtubule-IN-13 can be used for cancer research[1].

Product Specifications

UNSPSC

12352005

Target

Microtubule/Tubulin

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(C1=CC=C(C=C1F)C(F)(F)F)NC2=C(C3=CC=CC=C3NC2=O)O

Molecular Formula

C17H10F4N2O3

Molecular Weight

366.27

References & Citations

[1]Abushaikha G M, et al. Identification and Preliminary Characterization of a Novel Tasquinimod Analog that Unexpectedly Induces Mitotic Arrest by Alteration of Microtubule Dynamics[J]. ACS Medicinal Chemistry Letters, 2025.