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PARP1-IN-48

PARP1-IN-48 is a highly selective PARP1 (PARP1 IC50 = 3 nM, PARP2 IC50 = 170 nM) inhibitor. PARP1-IN-48 can be used for research on cancer, viral infections, and metabolic conditions[1].

Product Specifications

CAS Number

3085256-81-8

UNSPSC

12352005

Target

PARP

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Field of Research

Cancer; Infection; Metabolic Disease

Smiles

CCC(N1CCN(CC1)CC2=CC3=C(N=C2)C=C(C(N3)=O)CC)=S

Molecular Formula

C18H24N4OS

Molecular Weight

344.47

References & Citations

[1]Zhou X, et al. Synthesis of Novel PARP Inhibitors and Their Uses in Treatment of PARPs Related Diseases[J]. ACS Medicinal Chemistry Letters, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PARP1

Frequently Asked Questions

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