PARP1-IN-48
PARP1-IN-48 is a highly selective PARP1 (PARP1 IC50 = 3 nM, PARP2 IC50 = 170 nM) inhibitor. PARP1-IN-48 can be used for research on cancer, viral infections, and metabolic conditions[1].
Product Specifications
CAS Number
[3085256-81-8]
UNSPSC
12352005
Target
PARP
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer; Infection; Metabolic Disease
Smiles
CCC(N1CCN(CC1)CC2=CC3=C(N=C2)C=C(C(N3)=O)CC)=S
Molecular Formula
C18H24N4OS
Molecular Weight
344.47
References & Citations
[1]Zhou X, et al. Synthesis of Novel PARP Inhibitors and Their Uses in Treatment of PARPs Related Diseases[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP1
Curated Selection
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