HDAC11-IN-4
HDAC11-IN-4 is a potent and selective HDAC11 inhibitor with an IC50 of 13.49 nM and a Ki of 2.2 nM. HDAC11-IN-4 exhibits extremely high selectivity for HDAC11 over other defatty-acylases such as SIRT2, SIRT3, SIRT6, and HDAC8 (SI >10,000) . HDAC11-IN-4 can be used for the research of cancer[1].
Product Specifications
UNSPSC
12352005
Target
HDAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
CCCCCCCCCCCCSC[C@H](C(NCCCC[C@@H]1NC([C@@H](NC1=O)CCC(N)=O)=O)=O)N
Molecular Formula
C26H49N5O4S
Molecular Weight
527.76
References & Citations
[1]Sebastian Hilscher, et al. Substrate-Guided Development of HDAC11-Selective Inhibitors Featuring α-Amino Amide Zinc-Binding Groups. ACS Omega 2025, 10, 42, 50577–50587
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC11
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
