Nrf2 ligand-Linker Conjugate 2
Nrf2 ligand-Linker Conjugate 2 is a synthesized Nrf2 ligand-linker conjugate that can be used for synthesis of PROTAC K-Ras Degrader-7 (HY-178873) . PROTAC K-Ras Degrader-7 is a potent K-Ras PROTAC degrader with anti-tumor activity[1].
Product Specifications
Target
PROTAC-Linker Conjugates for PAC
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Field of Research
Cancer
Smiles
NCCOCCOC1=C2C(N=NN2C)=CC(C(C3=CC(CN4S(=O)(C5=CC=CC=C5O[C@@H](C4)C)=O)=C(C=C3)C)CC(O)=O)=C1
Molecular Formula
C31H37N5O7S
Molecular Weight
623.72
References & Citations
[1]Joel Austin, et al. Protac compounds binding keap1 ubiquitin ligase for targeted protein degradation. WO2025085815A1
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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