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E3 ligase Ligand 75

E3 ligase Ligand 75 is an E3 ligase ligand. E3 ligase Ligand 75 can be used for synthesis PROTAC K-Ras Degrader-7 (HY-178873) [1].

Product Specifications

CAS Number

[3063924-16-0]

UNSPSC

12352005

Target

Ligands for E3 Ligase

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

FC1=C(C2=CC(O)=CC3=C2C(C#C)=C(F)C=C3)N=CC4=C1N=C(N=C4N5CCC(CC5)C(O)=O)OC[C@@]67N(CCC7)C[C@@H](C6)F

Molecular Formula

C33H30F3N5O4

Molecular Weight

617.62

References & Citations

[1]Austin J, et al. PROTAC Compounds Binding Keap1 Ubiquitin Ligase for Targeted Protein Degradation. WO2025085815A1. 2025-04-24.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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