CNI-H0294 (hydrochloride)

CNI-H0294 hydrochloride is a selective HIV-1 integrase inhibitor. CNI-H0294 hydrochloride is promising for research of HIV-associated central nervous system diseases[1].

Product Specifications

CAS Number

[180740-99-2]

UNSPSC

12352005

Target

HIV; HIV Integrase

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection; Neurological Disease

Smiles

O=C(C)C1=CC(/N=C2N=C(N(C)C(C)=C\2)N)=CC(C(C)=O)=C1.Cl

Molecular Formula

C16H19ClN4O2

Molecular Weight

334.80

References & Citations

[1]Popov S, et al. Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation. Proc Natl Acad Sci U S A. 1996 Oct 15;93 (21) :11859-64.