3- (7-Methoxy-3-oxo-1H-isoindol-2-yl) piperidine-2,6-dione-azacyclohexane-C-piperazine-CO
3- (7-Methoxy-3-oxo-1H-isoindol-2-yl) piperidine-2,6-dione-azacyclohexane-C-piperazine-CO is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize PROTAC LRRK2 Degrader-4. PROTAC LRRK2 Degrader-4 is a potent LRRK2 PROTAC degrader with anti-neuroinflammatory activity[1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Neurological Disease
Smiles
COC1=C2C(C(N(C3C(NC(CC3)=O)=O)C2)=O)=CC=C1N(CC4)CCC4CN5CCN(C=O)CC5
Molecular Formula
C25H33N5O5
Molecular Weight
483.56
References & Citations
[1]Renner, A. C., et al. RRK2 Degraders for Parkinson’s Disease and Inflammation: Tau and α-Synuclein Degraders for Neurodegeneration. ACS Med. Chem. Lett.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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