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3- (7-Methoxy-3-oxo-1H-isoindol-2-yl) piperidine-2,6-dione-azacyclohexane-C-piperazine-CO

Selected Variant

HY-178832

Size: 1 Each

3- (7-Methoxy-3-oxo-1H-isoindol-2-yl) piperidine-2,6-dione-azacyclohexane-C-piperazine-CO is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize PROTAC LRRK2 Degrader-4. PROTAC LRRK2 Degrader-4 is a potent LRRK2 PROTAC degrader with anti-neuroinflammatory activity[1].

Product Specifications

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Neurological Disease

Smiles

COC1=C2C(C(N(C3C(NC(CC3)=O)=O)C2)=O)=CC=C1N(CC4)CCC4CN5CCN(C=O)CC5

Molecular Formula

C25H33N5O5

Molecular Weight

483.56

References & Citations

[1]Renner, A. C., et al. RRK2 Degraders for Parkinson’s Disease and Inflammation: Tau and α-Synuclein Degraders for Neurodegeneration. ACS Med. Chem. Lett.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Price

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