Azacyclohexane-O-cyclohexane-C- (OCH3) 2

Azacyclohexane-O-cyclohexane-C- (OCH3) 2 is a PROTAC linker that can be used to synthesize PROTAC LRRK2 Degrader-3 (HY-178797) . PROTAC LRRK2 Degrader-3 is a potent LRRK2 PROTAC degrader with anti-neuroinflammatory activity[1].

Product Specifications

CAS Number

[2839672-81-8]

UNSPSC

12352005

Target

PROTAC Linkers

Related Pathways

PROTAC

Field of Research

Neurological Disease

Smiles

COC(OC)[C@@H]1CC[C@@H](OC2CCNCC2)CC1

Molecular Formula

C14H27NO3

Molecular Weight

257.37

References & Citations

[1]Renner, A. C., et al. RRK2 Degraders for Parkinson’s Disease and Inflammation: Tau and α-Synuclein Degraders for Neurodegeneration. ACS Med. Chem. Lett.