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LSD1-IN-45

LSD1-IN-45 is an LSD1 inhibitor and a ligand for the target protein for PROTAC. LSD1-IN-45 can be used to synthesize PROTAC LD-110.

Product Specifications

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Related Pathways

PROTAC

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Smiles

O=C(O)C1=CC=C(C2=NC=C(OCC3CCNCC3)C=C2C4=CC=C(C#N)C=C4)C=C1

Molecular Formula

C25H23N3O3

Molecular Weight

413.47

References & Citations

[1]Zhuo J, et al. Discovery of LD-110 as an Effective LSD1 PROTAC Degrader for the Treatment of Esophagus Squamous Cancer. J Med Chem. 2025 Oct 23;68 (20) :21860-21877.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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