LSD1-IN-45
LSD1-IN-45 is an LSD1 inhibitor and a ligand for the target protein for PROTAC. LSD1-IN-45 can be used to synthesize PROTAC LD-110 (HY-178825) [1].
Product Specifications
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Related Pathways
PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(O)C1=CC=C(C2=NC=C(OCC3CCNCC3)C=C2C4=CC=C(C#N)C=C4)C=C1
Molecular Formula
C25H23N3O3
Molecular Weight
413.47
References & Citations
[1]Zhuo J, et al. Discovery of LD-110 as an Effective LSD1 PROTAC Degrader for the Treatment of Esophagus Squamous Cancer. J Med Chem. 2025 Oct 23;68 (20) :21860-21877.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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