AQ-13
AQ-13 (Compound 7) is a Chloroquine (HY-17589A) analogue with anti-breast cancer property. AQ-13 shows antiproliferative activities against MDA-MB231 and MCF7 with GI50 of 27.81 and 17.85 μM. AQ-13 shows low cytotoxicity against non-cancerous breast epithelial cells MCF10A (GI50 = 65.26 μM) . AQ-13 can be used for the research of breast cancer[1].
Product Specifications
CAS Number
[32571-49-6]
UNSPSC
12352005
Target
Drug Derivative
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
ClC1=CC2=NC=CC(NCCCN(CC)CC)=C2C=C1
Molecular Formula
C16H22ClN3
Molecular Weight
291.82
References & Citations
[1]Solomon VR, et al. Design and synthesis of chloroquine analogs with anti-breast cancer property. Eur J Med Chem. 2010 Sep;45 (9) :3916-23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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