SDH-IN-37

SDH-IN-37 (Compound A37) is a potent SDH inhibitor, with an IC50 value of 0.0263 μM. SDH-IN-37 is also an antifungal agent. SDH-IN-37 demonstrates antifungal activities against Rhizoctonia solani, S. sclerotiorum and F. graminearum, with EC50 values of 0.0144, 0.882 and 1.99 μg/mL, respectively[1].

Product Specifications

CAS Number

[3085095-58-2]

UNSPSC

12352005

Target

Fungal; Succinate Dehydrogenase

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Field of Research

Infection

Smiles

CN(C=C1C(C(CC2=CC(C3=CC(F)=C(C(F)=C3)F)=CC=C2)C#N)=O)N=C1C(F)F

Molecular Formula

C21H14F5N3O

Molecular Weight

419.35

References & Citations

[1]Cheng L, et al. Discovery of Novel Flexible β-Ketonitrile Derivatives Bearing a Biphenyl Moiety as Potential Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2025 Oct 15;73 (41) :25908-25915.