SDH-IN-37
SDH-IN-37 (Compound A37) is a potent SDH inhibitor, with an IC50 value of 0.0263 μM. SDH-IN-37 is also an antifungal agent. SDH-IN-37 demonstrates antifungal activities against Rhizoctonia solani, S. sclerotiorum and F. graminearum, with EC50 values of 0.0144, 0.882 and 1.99 μg/mL, respectively[1].
Product Specifications
CAS Number
[3085095-58-2]
UNSPSC
12352005
Target
Fungal; Succinate Dehydrogenase
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Smiles
CN(C=C1C(C(CC2=CC(C3=CC(F)=C(C(F)=C3)F)=CC=C2)C#N)=O)N=C1C(F)F
Molecular Formula
C21H14F5N3O
Molecular Weight
419.35
References & Citations
[1]Cheng L, et al. Discovery of Novel Flexible β-Ketonitrile Derivatives Bearing a Biphenyl Moiety as Potential Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2025 Oct 15;73 (41) :25908-25915.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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