Antileishmanial agent-37
Antileishmanial agent-37 (Compound 1b) is an antileishmanial agent, TbPTR1 (an IC50 value of 17.1 μM) and LmPTR1 inhibitor. Anti-leishmaniasis agent-37 has a moderate effect against Leishmania infantum[1].
Product Specifications
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
NC1=NC2=CC(C(N(CCC3=CC=C(C(Cl)=C3)Cl)C4CC4)=O)=CC=C2S1
Molecular Formula
C19H17Cl2N3OS
Molecular Weight
406.33
References & Citations
[1]Panecka-Hofman J, et al. Design of 2-Aminobenzothiazole Derivatives Targeting Trypanosomatid PTR1 by a Multidisciplinary Fragment Hybridization Approach. J Med Chem. 2025 Oct 9;68 (19) :20595-20618.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Leishmania
Curated Selection
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