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Antileishmanial agent-37

Antileishmanial agent-37 (Compound 1b) is an antileishmanial agent, TbPTR1 (an IC50 value of 17.1 μM) and LmPTR1 inhibitor. Anti-leishmaniasis agent-37 has a moderate effect against Leishmania infantum[1].

Product Specifications

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

NC1=NC2=CC(C(N(CCC3=CC=C(C(Cl)=C3)Cl)C4CC4)=O)=CC=C2S1

Molecular Formula

C19H17Cl2N3OS

Molecular Weight

406.33

References & Citations

[1]Panecka-Hofman J, et al. Design of 2-Aminobenzothiazole Derivatives Targeting Trypanosomatid PTR1 by a Multidisciplinary Fragment Hybridization Approach. J Med Chem. 2025 Oct 9;68 (19) :20595-20618.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Leishmania

Frequently Asked Questions

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