GABAA receptor modulator-11
GABAA receptor modulator-11 (Compound 4) is a GABAA receptor modulator. GABAA receptor modulator-11 inhibits anesthetic-induced desensitization of GABAA α1β3γ2 and α1β3 receptors, with IC50 values of 5.1 μM and 3.1 μM, respectively. GABAA receptor modulator-11 can be used for research on central nervous system diseases[1].
Product Specifications
UNSPSC
12352005
Target
GABA Receptor
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C1NC2(C(N1)=O)C3=CC=CC=C3C2
Molecular Formula
C10H8N2O2
Molecular Weight
188.18
References & Citations
[1]Koinas DA, et al. Spiro Hydantoins Can Reverse the Action of Positive Allosteric Modulators on GABAARs. ACS Med Chem Lett. 2025 Sep 30;16 (10) :2078-2083.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
041029-ML650 100 µL
RHO, CT (RHO, OPN2, Rhodopsin, Opsin-2) (MaxLight 650) discontinued
Ask
View Details 