DHFR-IN-5-amino-PEG3-C2-azido
DHFR-IN-5-amino-PEG3-C2-azido is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize BION106 (HY-178728) . BION106 is a potent DHFR-TS PROTAC degrader with anti-malarial activity[1].
Product Specifications
CAS Number
[3077918-53-4]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Infection
Smiles
CCC1=NC(N)=NC(N)=C1OCCCOC(C=CC=C2)=C2CCC(NCCOCCOCCOCCN=[N+]=[N-])=O
Molecular Formula
C26H40N8O6
Molecular Weight
560.65
References & Citations
[1]Nitipol SRIMONGKOLPITHAK, et al. HYBRID MOLECULES BETWEEN PYRIMIDINE DERIVATIVES AND IDASANUTLIN FIELD OF INVENTION. WO2025053796A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
P70503 250 Units/Pack
Weighing Boat with Pour Spout, PS, Small, 250 un. - ABDOS
Sign In for Pricing
View Details 
MBS9926281-03 5x 96 Well
Horse Karyopherin Alpha 4 (KPNA4) ELISA Kit
Sign In for Pricing
View Details 
MBS9926281-04 10x 96 Well
Horse Karyopherin Alpha 4 (KPNA4) ELISA Kit
Sign In for Pricing
View Details