DHFR-IN-5-amino-PEG3-C2-azido
DHFR-IN-5-amino-PEG3-C2-azido is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize BION106 (HY-178728) . BION106 is a potent DHFR-TS PROTAC degrader with anti-malarial activity[1].
Product Specifications
CAS Number
[3077918-53-4]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Field of Research
Infection
Smiles
CCC1=NC(N)=NC(N)=C1OCCCOC(C=CC=C2)=C2CCC(NCCOCCOCCOCCN=[N+]=[N-])=O
Molecular Formula
C26H40N8O6
Molecular Weight
560.65
References & Citations
[1]Nitipol SRIMONGKOLPITHAK, et al. HYBRID MOLECULES BETWEEN PYRIMIDINE DERIVATIVES AND IDASANUTLIN FIELD OF INVENTION. WO2025053796A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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