AChE-IN-96

AChE-IN-96 (Compound 8a) is an AChE inhibitor, with an IC50 of 0.697 μM. AChE-IN-96 can be used for the study of neurodegenerative diseases such as Alzheimer's disease (AD) [1].

Product Specifications

UNSPSC

12352005

Target

Cholinesterase (ChE)

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Smiles

O=C(NC1=CC=C(C)C=C1C)CSC2=NN=C(COC3=CC=C4C=CC=CC4=C3)N2C5=CC=CC=C5

Molecular Formula

C29H26N4O2S

Molecular Weight

494.61

References & Citations

[1]Ayub M, et al. Design, Synthesis, and Computational Studies of Novel N- (Substituted phenyl) -3- (5- ((naphthalen-2-yloxy) methyl) -4-phenyl‑4H‑1,2,4-triazol-3-ylthio) acetamides as Potent Acetylcholinesterase Inhibitors. ACS Omega. 2025 Sep 29;10 (39) :45191-45203.